TABLE 5.
Eligible patient analysis parametera | No. % of patients with end point posttreatment
|
Pb | |
---|---|---|---|
Itraconazole (n = 201) | Amphotericin B (n = 186) | ||
Invasive aspergillosis | 5 (2.5)c | 9 (4.8)d | 0.216 |
Proven deep fungal infection (including invasive aspergillosis) | 8 (4.0)c | 12 (6.5)e | 0.273 |
Superficial fungal infection | 2 (1.0) | 11 (5.9) | 0.007 |
Total proven fungal infection | 10 (5.0) | 23 (12.4) | 0.009 |
Suspected deep fungal infection (including fever of unknown origin) | 75 (37.3) | 73 (39.2) | 0.696 |
Patients were classified as eligible with a neutrophil count of <0.5 × 109/liter for at least 14 days.
Intergroup comparison, chi-square test.
One died.
Four died.
Five died.