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. 2022 Apr 2;14(7):1813. doi: 10.3390/cancers14071813

Table 3.

Summary of 279 EMT genes with up-streaming or down-streaming associated with NSCLC evolution.

ACTA1 Inline graphic CDC42 Inline graphic ELMO3 * GRHL2 * LTBP4 * PARP1 Inline graphic SH3YL1 * TIMP1 Inline graphic
ACTN1 * CDH1 *^” Inline graphic EPB41L5 * GSC Inline graphic MAF * PDGFB Inline graphic SHANK3 * TIMP2 *
ADGRF4 * CDH2 ”^ Inline graphic EPHA1 * GSK3B Inline graphic MAL2 * PDLIM7 * SHROOM3 * TJP1 ”
AFAP1L2 * CDH3 * EPHB2 * HNMT * MAP1B Inline graphic PEA15 * SIP1 Inline graphic TJP3 *
AHNAK Inline graphic CDS1 * EPN3 * HRG Inline graphic MAPK13 * PIK3CD * SKIL * TMC4 *
AKT1 Inline graphic CERCAM * EPPK1 * IGFBP4 Inline graphic MAPRE2 * PLAUR * SMAD2 Inline graphic TMC5 *
ANGPTL4 Inline graphic CHST3 * ERBB3 * Inline graphic IGFBP5 Inline graphic MBOAT2 * PLEK2 * Inline graphic SMAD3 Inline graphic TMEFF1 Inline graphic
ANKLE2 * CLDN12 Inline graphic ESR1 Inline graphic IL11 * METRNL * PLG Inline graphic SMAD7 * TMEM125 *
ANKRD22 * CLDN23 Inline graphic EVPL * IL1RN Inline graphic MITF Inline graphic PMEPA1 * SNAI1 *^” Inline graphic TMEM132A Inline graphic
ANTXR2 * CLDN3 Inline graphic EXOC6 * ILK Inline graphic MLXIP * PPARG * SNAI2 ^” Inline graphic TMEM30B *
AP1M2 * CLDN4 * Inline graphic EZH1 Inline graphic INADL * Inline graphic MMP10 Inline graphic PPP1R13L * SNAI3 Inline graphic TMEM45B *
ARHGEF18 * CLDN7 * Inline graphic EZH2 Inline graphic INHBA Inline graphic MMP2 ”* Inline graphic PPP1R18 * SOX10 ” TNFRSF21 *
ARHGEF40 * CMTM3 * F11R * Inline graphic ITBG6 ” MMP3 ” Inline graphic PPPDE2 Inline graphic SOX11 Inline graphic TP53I3 *
AXL * COL1A1 * FGF1 Inline graphic ITGA5 * Inline graphic MMP9 ” Inline graphic PRR5 * SPARC Inline graphic TPM1 *
BCL2 Inline graphic COL1A2 Inline graphic FGF5 Inline graphic ITGAV Inline graphic MPP7 * PRSS22 * SPINT2 * TRIO *
BCL9 Inline graphic COL3A1 Inline graphic FGFBP1 Inline graphic ITGB1 Inline graphic MPZL2 * PRSS8 * SPP1 Inline graphic TRMT10A *
BEAN1 * COL5A1 Inline graphic FGFR1 * ITGB3 Inline graphic MSN Inline graphic PTK2 Inline graphic SSH3 * TSPAN13 Inline graphic
BICDL1 * COL7A1 * FHL1 Inline graphic ITGB6 * MST1R Inline graphic PTP4A1 Inline graphic ST14 * TSPAN2 *
BIRC3 Inline graphic CRB3 * Inline graphic FLNA * Inline graphic JAG1 Inline graphic MTA3 Inline graphic PTRF * STAP2 * TWIS1 ”
BMP1 * Inline graphic CTGF Inline graphic FN1 ” Inline graphic JUNB * MTAC2D1 * PXDC1 * STAT3 Inline graphic TWIST1 Inline graphic
BMP7 Inline graphic CTNNA1 * FOXC2 Inline graphic JUP * MUC1 * PXN Inline graphic STEAP1 Inline graphic VCAN * Inline graphic
BSPRY * CTNNB1 Inline graphic FOXC2 ” KCTD11 * MUC5AC * PXN-AS1 * TACSTD1 * VIM *^” Inline graphic
C1ofr116 * DACT1 Inline graphic FRMD6 * KLC3 * MUC5B * RAB25 * TACSTD2 * VPS13A Inline graphic
C1ofr171 * DBN1 * FXYD3 * KLF7 * NAV1 * RAC1 Inline graphic TBC1D30 * WEE1 Inline graphic
C3orf21 * DCN Inline graphic FZD7 Inline graphic KRT14 Inline graphic NCOR2 * RBM35A * TCF3 Inline graphic WNT11 Inline graphic
CALCR Inline graphic DEPTOR * GADD45A Inline graphic KRT7 Inline graphic NF1 * RBPMS * TCF4 Inline graphic WNT2B Inline graphic
CALD1 * Inline graphic DHFR Inline graphic GADD45B * Inline graphic KRTCAP3 * NKAIN4 * RGS2 Inline graphic TFPI Inline graphic WNT5A Inline graphic
CAMK2N1 Inline graphic DLG1 Inline graphic GALNT2 * KTR19 * NLK Inline graphic RHOD * TFPI2 Inline graphic WNT5B Inline graphic
CARD6 * DSC2 Inline graphic GALNT3 * LAMB3 Inline graphic NODAL Inline graphic S100A14 * TGFB1 * Inline graphic WNT7A *
CASP3 Inline graphic DSP *” Inline graphic GALNT5 * LAMC2 * NOTCH1 Inline graphic SAMD4A * TGFB1I1 * WT1 Inline graphic
CAV2 Inline graphic EEPD1 * GNC ” LIX1L * NPPB Inline graphic SCARB2 Inline graphic TGFB2 Inline graphic YWHAG Inline graphic
CCNB2 Inline graphic EGF Inline graphic GNG11 Inline graphic LOXL2 Inline graphic NRG1 Inline graphic SCNN1A * TGFB3 Inline graphic ZEB1 *^ Inline graphic
CCND1 Inline graphic EGFR Inline graphic GPR110 * LRRC54 * NRP1 * SCRIB Inline graphic TGFBR1 * ZEB2 ^ Inline graphic
CD36 Inline graphic EHF * GPR56 * LTBP1 * NUDT13 Inline graphic SERINC2 * THBS1 Inline graphic ZFP36L1 *
CD47 Inline graphic ELANE Inline graphic GRHL1 * LTBP3 * OCLN Inline graphic SERPINE1 * Inline graphic THRB *

Inline graphic genes described in the literature [102]; * genes whose contribution was evaluated by microarrays [103,104,105], ^ genes whose contribution was evaluated by qPCR [106], ” genes whose contribution was evaluated by RNAseq [107].