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. 2022 Mar 28;19(7):4005. doi: 10.3390/ijerph19074005

Table 1.

COVID-19 disease classification, signs and symptoms, and antibiotic use according to the 2020 WHO clinical management guidelines.

Disease Severity Signs and Symptoms Antibiotic Use
Asymptomatic No symptoms No
Mild Fever, cough, fatigue, anorexia, shortness of breath, myalgia No
Moderate Fever, cough, dyspnoea, fast breathing, SpO2 ≥ 90% on room air Yes, only if suspicion of bacterial infection
Severe Fever, cough, dyspnoea, fast breathing, respiratory rate > 30 breaths/min, severe respiratory distress, SpO2 < 90% on room air Yes, only if suspicion of bacterial infection
Critical Lobar or lung collapse, respiratory failure, PaO2/FiO2a ≤ 300 mmHg- PaO2/FiO2 ≤ 100 mmHg, acute life-threatening organ dysfunction, fast heart rate, weak pulse, cold extremities or low blood pressure, skin mottling, coagulopathy, thrombocytopenia, acidosis, high lactate, or hyperbilirubinemia. Yes, within one hour of admission

SpO2—Oxygen saturation; PaO2—Partial pressure of oxygen; FiO2—Fraction of inspired oxygen.