Figure 3.

Antitumor activity of BPA, TMZ, and TMZB with or without BNCT. (a) HS683 cell viability was measured with a CCK8 assay, where cells were treated with 1.0 μmol/mL of BPA, TMZ, or TMZ-B. (b) Clonogenic surviving fractions of HS683 cells treated with various concentrations of BPA, TMZ, or TMZB without BNCT. (c) Clonogenic surviving fractions of HS683 cells treated with various concentrations of BPA-, TMZ-, or TMZB-based BNCT. The IC50 was calculated using Prism8 software. The statistical comparisons between curves were carried out using the Wilcoxon signed rank test and survival curve. * p < 0.05, ** p < 0.01.