Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 28;11(7):1135. doi: 10.3390/cells11071135

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Successful methods of deriving oocytes in vitro from mouse pluripotent stem cells. Cells originated from mouse embryonic stem cells (mESCs) or mouse-induced pluripotent stem cells (miPSCs) developed into primordial germ cell-like cells (PGCLCs) and differentiated into oocytes either by aggregating with in vivo-derived fetal gonadal somatic cells or with fetal ovarian somatic cell-like cells (FOSLCs), after transplant into the ovarian bursa or by generating reconstituted ovary (rOvary) containing growing oocytes. All of these strategies led to producing live offspring [80,82,85].