Skip to main content
. 2022 Mar 22;11(7):1071. doi: 10.3390/cells11071071

Figure 1.

Figure 1

LPA5 deletion attenuates peripheral TNFα and IL-1β concentrations in LPS-injected mice. Wt and LPA5-/- mice were injected i.p. with PBS (n = 4) or LPS (5 mg/kg; n = 6). After 24 h, the animals were sacrificed, blood was collected and serum was isolated. The concentrations of (A) TNFα, (B) IL-6, and (C) IL-1β were quantified using ELISAs. Values are expressed as mean ± SEM, * p < 0.05, **** p < 0.0001 compared to wt PBS control; &&& p < 0.001 compared to LPA5-/- PBS control; # p < 0.05, ## p < 0.01 compared to LPS-treated wt mice; two-way ANOVA with Bonferroni correction).