Table 1.
Effect of lipopolysaccharide (LPS) administration (10 mg/kg ip.) on body weight gain, diaphragm and gastrocnemius weights, serum concentrations of urea, creatinine, glucose, lactate, bicarbonate (HCO3−), partial pressure of carbon dioxide oxygen (PaCO2), oxygen (PaO2), and soluble oxygen SO2 and pH in arterial blood. The data represent mean ± standard error of the mean (SEM). ** p < 0.01 versus control rats treated with saline.
| Control, n = 9 | LPS, n = 8 | |
|---|---|---|
| Body weight gain (g/24 h.) | −2.0 ± 0.9 | −21.9 ± 3.6 ** |
| Diaphragm (mg/100 g b.w.) | 206 ± 15 | 232 ± 17 |
| Gastrocnemius (mg/100 g b.w.) | 520 ± 20 | 517 ± 10 |
| Urea (mg/dL) | 22.1 ± 1.7 | 49.8 ± 5.9 ** |
| Creatinine (mg/dL) | 0.208 ± 0.008 | 0.331 ± 0.03 ** |
| Glucose (mg/dL) | 234 ± 8 | 180 ± 16 ** |
| Lactate (mmol/L) | 1.6 ± 0.2 | 5.6 ± 0.8 ** |
| HCO3- (mmol/L) | 26.0 ± 0.6 | 18.0 ± 2.2 ** |
| PaCO2 (mmHg) | 42.7 ± 3.9 | 37.8 ± 5.6 |
| PaO2 (mmHg) | 86.0 ± 6.1 | 88.0 ± 6.6 |
| SO2% (mmol/L) | 95.0 ± 1.3 | 95 ± 0.9 |
| pH | 7.39 ± 0.03 | 7.30 ± 0.04 |