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. 2022 Mar 30;23(7):3788. doi: 10.3390/ijms23073788

Figure 3.

Figure 3

BHB increases the expression of cholesterol transporters and attenuates foam cell for-mation. (A) Western blot analysis of the protein expression of cellular cholesterol transporters including ABCA1, ABCG1, and SR-B1 in PMs treated with OxLDL (50 μg/mL) and BHB (0.5 mM, 1 mM) for 24 h. (B) Quantification of relative protein expression (n ≥ 3). (C) Oil Red O staining of PMs in the presence or absence of OxLDL (50 μg/mL) or BHB for 24 h. Scale bars, 5 μm. (D) Quantification of Oil Red O staining (n = 6). Data are represented as means ± SEM. * p < 0.05, ** p < 0.01 vs. control; # p < 0.05, ## p < 0.01 vs. OxLDL treated group.