Table 4.

Clinical studies included in the systematic review.

No.	Study Type	Analyzed Samples	Study Endpoint	IL-22 Role
5 [15]	Cohort observational study	Peritoneal drainage fluid	The function of IL-22 in peritoneal adhesions formation	IL-22 promoted adhesion formation
6 [16]	Comparative observational study	Cervical drainage fluid	Cytokines and growth factors levels in slow versus fast wound healing	High IL-6 and VEGF-A levels in the postoperative wound fluid of cervical lymph node tuberculosis patients correlate with delayed wound healing.
7 [17]	Comparative observational study	Skin biopsy	In situ mRNA expression of growth factors and cytokines in keloid and normal scars	Significant high expression of TGF-ß, IL-22, and ARG-1 was found in keloid scars