Table 1.
Clinical and pathological characteristics of the 47 Romanian patients with primary BC and BRCA mutations selected by age at diagnosis and tumor characteristics.
| Age (Years) | Number | Percentage |
|---|---|---|
| <40 | 26 | 55% |
| 41–60 | 17 | 36% |
| >60 | 4 | 9% |
| Bilateral BC | ||
| Yes | 9 | 19% |
| No | 38 | 81% |
| TNBC | ||
| Yes | 26 | 55% |
| No | 18 | 38% |
| Unknown | 3 | 7% |
| Tumor hormone receptor status | ||
| ER | ||
| Positive | 19 | 40% |
| Negative | 27 | 57% |
| Unknown | 1 | 3% |
| PR | ||
| Positive | 16 | 34% |
| Negative | 28 | 59% |
| Unknown | 3 | 6% |
| HER2 status | ||
| Positive | 6 | 12% |
| Negative | 36 | 76% |
| Unknown | 5 | 12% |
| Stage at diagnosis | ||
| I | 3 | 6% |
| II | 24 | 51% |
| III | 11 | 23% |
| Unknown | 9 | 19% |
| Grade | ||
| 2 | 11 | 23% |
| 3 | 30 | 64% |
| Unknown | 6 | 13% |
| Total | 47 patients 100% | |