Table 7.
Mutation | Frequency | Percentage | BRCA1 | BRCA2 |
---|---|---|---|---|
Frameshift duplication | 10 | 17% | 8 | 2 |
Frameshift insertion | 2 | 3% | 0 | 2 |
Frameshift deletion | 8 | 14% | 5 | 3 |
Frameshift indel | 1 | 2% | 0 | 1 |
Frameshift splice donor | 1 | 2% | 1 | 0 |
Frameshift splice acceptor | 2 | 3% | 2 | 0 |
Frameshift microsatellite | 1 | 2% | 1 | 0 |
Nonsense deletion | 1 | 2% | 0 | 1 |
Nonsense | 17 | 30% | 17 | 0 |
Missense | 13 | 23% | 6 | 7 |
Single nucleotide variant | 1 | 2% | 1 | 0 |