CAFs |
cancer-associated fibroblasts |
CTLs |
cytotoxic T lymphocytes |
CTLA-4 |
cytotoxic T lymphocyte antigen-4 |
ECM |
extracellular matrix |
EGF |
epidermal growth factor |
EMT |
epithelial-mesenchymal transition |
HBV |
hepatitis B virus |
HCC |
hepatocellular carcinoma |
HCV |
hepatitis C virus |
HGF |
hepatocyte growth factor |
HIF |
hypoxia-inducible factor |
HSC |
hepatocyte stellate cells |
IDO |
indoleamine 2,3-dioxygenase |
IFN |
interferon |
IL |
interleukin |
KC |
Kupffer cells |
LSECs |
liver sinusoidal endothelial cells |
MoMΦs |
monocyte-derived macrophages |
MTA |
methylthioadenosine |
NAFLD |
non-alcoholic fatty liver disease |
NASH |
non-alcoholic steatohepatitis |
NETs |
neutrophil cellular traps |
NK |
natural killer |
OS |
overall survival |
PD-1 |
programmed cell death protein 1 |
PD-L1 |
programmed cell death ligand 1 |
PDGF |
platelet-derived growth factor |
PFS |
progression free survival |
PGE2 |
prostaglandin E2 |
ROS |
reactive oxygen species |
SAM |
S-adenosyl-L-methionine |
TAMs |
tumor-associated macrophages |
TANs |
tumor-associated neutrophils |
TGF |
transforming growth factor |
TME |
tumor microenvironment |
TNF |
tumor necrosis factor |
Tregs |
regulatory T cells |
VEGF |
vascular endothelial growth factor |