AD |
Alzheimer’s disease |
Aβ |
amyloid β-protein |
APP |
amyloid precursor protein |
Atg8 |
autophagy-related protein 8 |
AVs |
autophagic vacuoles |
APLP1 |
amyloid beta precursor-like protein 1 |
Atg39 |
autophagy-related protein 39 |
ALFY |
WD repeat and FYVE domain containing 3 |
ATGL |
adipose triglyceride lipase |
ATM |
ataxia-telangiectasia mutated |
BNIP3 |
E1B 19 kDa protein-interacting protein 3 |
BNIP3L |
adenovirus E1B 19kDa interacting protein 3-like |
Bre5 |
UBP3-associated protein BRE5 |
BACE1 |
beta-site APP-cleaving enzyme 1 |
CMA |
chaperone-mediated autophagy |
CHIP |
C-terminus of Hsc70-interacting protein |
CCPG1 |
cell cycle progression protein 1 |
ER |
endoplasmic reticulum |
ERAD |
ER-associated degradation |
FIP200 |
focal adhesion kinase family-interacting protein of 200 kDa |
FBXO27 |
F-box protein |
FKBP8 |
FKBP prolyl isomerase 8 |
G3BP1 |
G3BP stress granule assembly factor 1 |
Galectin 3 |
LGALS3/GAL3 |
TRIM16 |
tripartite motif containing 16 |
HDAC6 |
histone deacetylase 6 |
Hsc70 |
heat shock cognate protein 70 |
HSP60 |
heat shock cognate protein 60 |
HSP90 |
heat shock cognate protein 90 |
HSPs |
heat shock proteins |
LDs |
lipid droplets |
LMNB1 |
lamin B1 protein |
LC3 |
microtubule-associated proteins light chain 3 |
MFN1/2 |
mitofusin 1 and 2 |
Drp1 |
dynamin-related protein 1 |
NUFIP1 |
nuclear fragile X mental retardation-interacting protein 1 |
NM-DARS |
n-methyl-D-aspartate receptors |
NFTs |
neurofibrillary tangles |
Nvj1 |
nucleus–vacuole junction protein 1 |
NBR1 |
neighbor of BRCA1 gene 1 |
NLRP3 |
NLR family pyrin domain containing 3 |
Opa1 |
optic atrophy 1 |
PHFs |
paired helical filaments |
PINK1 |
PTEN-induced kinase 1 |
PGC-1-alpha |
peroxisome proliferator-activated receptor gamma coactivator 1 |
PTMs |
post-translational modifications |
PEX5 |
peroxisomal biogenesis factor 5 |
PEX2 |
peroxisomal biogenesis factor 2 |
PD |
Parkinson’s disease |
PPAR/PPARα |
peroxisome proliferator activated receptor alpha |
PI3P |
phosphatidylinositol 3-phosphate |
P-tau |
phosphorylated tau |
ROS |
reactive oxygen species |
RTN3 |
reticulon 3 |
P62 |
SQSTM1-p62 |
SEC62 |
preprotein translocation factor |
RB1CC1 |
RB1-inducible coiled-coil 1 |
TBK1 |
serine/threonine protein kinase |
TCA |
tricarboxylic acid cycle |
UPS |
ubiquitin–proteasome system |
UBA |
ubiquitin-associated domains |
UCHL1 |
ubiquitin carboxyl-terminal hydrolase L1 |
ULK1 |
Unc-51-like autophagy activating kinase 1 |
UBP3 |
ubiquitin carboxyl-terminal hydrolase 3 |
USP10 |
ubiquitin-specific protease 10 |
UPR |
unfolding protein response |
VDAC1 |
voltage-dependent anion-selective channel 1 |
VPS34 |
vacuolar protein sorting 34 |
Vac8 |
vacuole related 8 |
VCP |
valosin-containing protein. |