Figure 3.

Phylogenetic analysis of RLRs based on C-terminal conserved domain RIG-I_C-RD. Maximum likelihood trees were constructed using IQ-TREE. The species used for the tree generation were 30 lophotrochozoans (as shown in Figure 1), the poriferan A. queenslandica, cnidaria, and the chordate Homo sapiens. The lophotrochozoan RLRs can be majorly classified into two divergent classes, Cluster I and Cluster II. The background color on the gene name represents the phylum to which it belongs, as shown in the legend ‘Species’. The different colored shapes in the outer circles represent different types of domains, as shown in the legend ‘Domain’.