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. 2022 Mar 31;23(7):3862. doi: 10.3390/ijms23073862

Figure 1.

Figure 1

(a) Results of the Y2H assay of dimerization activity of the CLAMP N-terminal region shown for the domain structure of the CLAMP protein. AD stands for GAL4 activation domain and BD stands for GAL4 DNA-binding domain. Positive interaction indicates the ability of yeast to grow on assay plates without histidine. Assay plates are shown in Figure S2. (b) Multiple sequence alignment of N-terminal domains of CLAMP proteins from various insects performed with ClustalW [47]. The positions of predicted secondary structure, dimerization, and zinc-finger domains are shown. Residue numbering corresponds to D. melanogaster CLAMP.