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. 2022 Mar 29;23(7):3754. doi: 10.3390/ijms23073754

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Relationship between BRCA1/2 mRNA expression and clinical outcomes in breast cancer patients (PrognoScan Database, R2: Kaplan Meier Scanner and Kaplan–Meier Plotter). (a,b,e,f) The survival curve comparing the patient with high (red), and low (blue) expression of BRCA1/2 was plotted from the PrognoScan database (http://dna00.bio.kyutech.ac.jp/PrognoScan/, accessed on 10 February 2022) in breast cancer patients. The threshold of cox p value < 0.05. (c,g) The survival curve comparing the patient with high (red) and low (blue) expression of BRCA1/2 was plotted from R2: Kaplan Meier Scanner (https://hgserver1.amc.nl/cgi-bin/r2/main.cgi, accessed on 10 February 2022) in TCGA breast cancer patients. The threshold of cox p value < 0.05. (d,h) The survival curve comparing the patient with high (red) and low (black) expression of BRCA1/2 was plotted from Kaplan–Meier Plotter (https://kmplot.com/analysis/, accessed on 10 February 2022) in breast cancer patients. The threshold of cox p value < 0.05.