Table 2.
The relationships between BRCA1/2 expression and clinicopathological features in Breast Cancer.
| Variables | No. | BRCA1 (p Value) | BRCA2 (p Value) |
|---|---|---|---|
| Age | NS | p < 0.01 | |
| ≤60 | 601 | ||
| >60 | 482 | ||
| T-Stage | NS | NS | |
| T1 | 277 | ||
| T2 | 629 | ||
| T3 | 139 | ||
| T4 | 35 | ||
| N-Stage | p < 0.05 | p < 0.01 | |
| N0 | 514 | ||
| N1 | 358 | ||
| N2 | 116 | ||
| N3 | 76 | ||
| M-Stage | NS | NS | |
| M0 | 902 | ||
| M1 | 20 | ||
| ER status | p < 0.01 | p < 0.001 | |
| − | 240 | ||
| + | 793 | ||
| PR status | p < 0.001 | p < 0.001 | |
| − | 342 | ||
| + | 688 | ||
| HER2 status | NS | p < 0.01 | |
| − | 558 | ||
| + | 157 | ||
| PAM (50) | p < 0.001 | p < 0.001 | |
| Lum A | 562 | ||
| Lum B | 204 | ||
| Her 2 | 82 | ||
| Basal | 195 | ||
| Normal | 40 |
T stage: primary tumor, N stage: regional lymph nodes, M stage: distant metastasis, ER status: estrogen receptor, PR status: progesterone receptor, HER2 status: human epidermal growth factor receptor 2, PAM (50): prediction analysis of microarray 50, Lum A: luminal A, Lum B: luminal B, Her2: Her2-enriched, Basal: basal-like, Normal: normal-like, NS: no significance.