Figure 2.

Host interaction in Chlamydia and herpes simplex. (a) Chlamydia life cycles alternate between the elementary bodies and the reticulate bodies. Chlamydiosis inflammation may resolve with local scarring. (b) Herpes simplex virus binds pattern recognition receptors (PRRs) and stimulates IFN (α, β, γ) production. Following proliferation within the epidermal keratinocytes and Langerhans cells, the herpes virus undergoes anterograde transportation and enters the dormant stage inside the dorsal root ganglia. ISG = interferon-stimulated genes; PRR = pattern recognition receptor.