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. 2022 Mar 31;23(7):3847. doi: 10.3390/ijms23073847
4E-BP1 Eukaryotic translation initiation factor 4E-binding protein 1
ADCs Antibody–drug conjugates
AEG-1 Astrocyte elevated gene-1
AKT RAC-alpha serine/threonine-protein kinase
ANCs Antibody–nanoparticle conjugates
ARP2/3 Arp2/3 complex 34 kDa subunit
ASK1 Apoptosis signal-regulating kinase 1
ATF2 Cyclic AMP-dependent transcription factor 2
BCL-2 Apoptosis regulator Bcl-2
BCL-xL Antiapoptotic protein BCL-xL
BM Basement membrane
BRAF Serine/threonine-protein kinase B-raf
CAF Cancer-associated fibroblasts
CBD p300-P/CAF binding domain
CCT Chaperonin-containing TCP1 complex
C/EBPα CCAAT/enhancer-binding protein alpha
CASP8 Caspase 8
CCDC134 Coiled-coil domain-containing protein 134
CD31 Vascular endothelial cluster of differentiation 31
CDC25A M-phase inducer phosphatase 1
CDC42 Cell division control protein 42 homolog
CDK Cyclin-dependent kinases
CDKN2A Cyclin-dependent kinase inhibitor 2A
CID CtBP interaction domain
COX2 Cyclooxygenase-2
CRC Colorectal cancer
CSCs Cancer-stem cells
CTCs Circulating tumor cells
CXCL12 Stromal cell-derived factor 1
CXCR4 C-X-C chemokine receptor type 4
DDR1 Discoidin domain receptor 1
DIA1 Formin diaphanous 1
DNMT1 DNA methyltransferase 1
ECM Extracellular matrix
EGF Epidermal growth factor
EGFR Epidermal growth factor receptor
eIF-4E Eukaryotic translation initiation factor 4E
ELK-1 ETS domain-containing protein
EMT Epithelial–mesenchymal transition
ERK1/2 Extracellular signal-regulated kinase 1/2
ESR Estrogen receptor
FA Focal adhesions
FAK Focal adhesion kinase
FGFR1 Fibroblast growth factor receptor 1
FHC Ferritin heavy chain
FOX Forkhead box
FOXC1/2 Forkhead box protein C1/2
FRA1/2 FOS-related antigen 1/2
FYN SRC family tyrosine kinase FYN
GAPs GTPase-activating proteins
GBC Gallbladder cancer
GC Gastric cancer
GDIs Guanine nucleotide dissociation inhibitors
GEFs Guanine nucleotide exchange factors
GLI2 Glioma-associated oncogene homolog 2
GLS Glutaminase
GLUL Glutamine synthetase
GLUT Glucose transporters
GPCRs G protein-coupled receptors
GRB2 Growth factor receptor-bound protein 2
GRP94 Glucose-regulated protein 94
HCC Hepatocellular carcinoma
HDAC Histone deacetylase 1
HER2 Human epidermal growth factor receptor 2
HIF1α Hypoxic-responsive transcription factor α
HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1
HRE HIF-responsive element
HSP27 Heat-shock protein 27
IL Interleukin
I-SMAD Inhibitory SMADs
JIPs JNK-interacting proteins
JNK c-Jun N-terminal kinase
KRAS GTPase KRas
LAT1 Large neutral amino acid transporter 1
LIMK1 LIM domain kinase 1
MAP Microtubule-associated protein
MAPK Mitogen-activated protein kinase
MAPKK Mitogen-activated protein kinase kinase
MAPKKK Mitogen-activated protein kinase kinase kinase
MCT Monocarboxylate transporters
MEF Mouse embryonic fibroblasts
MEK1 MAPK/ERK kinase 1
MEKK1 Mitogen-activated protein kinase kinase kinase 1
MET Mesenchymal–epithelial transition
MK2/3 MAP kinase-activated protein kinase 2/3
MLC2 Myosin II light chain
MLCP Myosin-light-chain phosphatase
MLK3 Mitogen-activated protein kinase kinase kinase 11
MMPs Matrix metalloproteinases
MNK MAP kinase interacting kinase
MnSOD Manganese superoxide dismutase
MRCK Myotonic dystrophy kinase-related Cdc42-binding kinase
MSK1 Ribosomal protein S6 kinase alpha-5
mTOR Serine/threonine-protein kinase mTOR
MYC MYC proto-oncogene protein
NAIF1 Nuclear apoptosis-inducing factor 1
NCAM Neural cell adhesion molecule
NFκB Nuclear factor kappa B subunit
NHE Sodium hydrogen ion exchangers
PDGF-D Platelet-derived growth factor D
PDGFR Platelet-derived growth factor receptor
PDK1 3-Phosphoinositide-dependent protein kinase 1
PECAM Platelet and endothelial cell adhesion molecule 1
PI3K Phosphatidylinositol-4,5-bisphosphate 3-kinase
PIK3CA Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PKC Protein kinase C
PLC Phospholipase C
PPP2CA Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
PRL3 Protein tyrosine phosphatase type IVA 3
PRRX1 Paired mesoderm homeobox protein 1
PTEN Phosphatase and tensin homolog
PMCA4b Plasma membrane Ca2+ pump isoform 4b
PTHrP Parathyroid hormone-related protein
R-SMAD Receptor-activated SMADs
RAP1A Ras-related protein Rap-1A
RAC1 Ras-related protein RAC1
RAF Proto-oncogene serine/threonine-protein kinase RAF
RANK Tumor necrosis factor superfamily member 11
RANKL Tumor necrosis factor ligand superfamily member 11
RASAL1 RasGAP-activating-like protein 1
RB Retinoblastoma protein
RHOA Transforming protein RhoA
RHOE RHO-related GTP-binding protein E
ROCK RHO-associated kinase
ROS Reactive oxygen species
RPS6KA5/4 Ribosomal protein S6 kinase alpha-5/4
RTK Receptor tyrosine kinase
S6K Ribosomal protein S6 kinase
SID Smad interaction domain
SHCA SRC homology 2 domain-containing-transforming A
SFPQ Polypyridine tract-binding protein-associated splicing factor
SLC4/6 Sodium-coupled bicarbonate transporters
SMAD Mothers against decapentaplegic
SNAT2 Sodium-coupled neutral amino acid transporter 2
SOS Son of sevenless
SPRY2 Sprouty 2
STAT3 Signal transducer and activator of transcription 3
TAK1 Transforming growth factor-β-activated kinase 1
TAM Tumor-associated macrophage
TCA Tricarboxylic acid
TGFα/β Transforming growth factor alpha/beta
TICs Tumor-initiating cells
TIMPs Tissue inhibitors of metalloproteinases
TME Tumor microenvironment
TNBC Triple-negative breast cancer
TNC Tenascin-C
TNFα Tumor necrosis factor alpha
TP53 Cellular tumor antigen p53
TRAF6 TNF receptor-associated factor 6
TWIST1 Twist-related protein 1
TβR1/2 TGF-β type receptor 1/2
uPA Urokinase plasminogen activator
V-ATPase Vacuolar-type H+-adenosine triphosphatases
VEGF Vascular endothelial growth factor
VEGFR Vascular endothelial growth factor receptor
VHL Von Hippel–Lindau tumor suppressor
WASP Wiskott–Aldrich syndrome protein
ZEB1/2 Zinc finger E-box-binding homeobox 1/2
ZIC1 Zinc finger protein ZIC1