Figure 10.

Cardiotoxic effects induced by immunomodulatory tribodies or the combination of their respective parental compounds on human fetal cardiomyocytes. The lysis of HFC cells, co-cultured with hPBMCs in the absence (white bars) or presence of tribodies (striped bars) or the combinations of their respective compounds (grey bars) for 24 h, was analyzed by measuring the release of LDH in the supernatants of cultures. The values are reported as the mean of at least three determinations obtained in three independent experiments. Error bars depict means ± SD. p-value: *** p ≤ 0.001; * p < 0.05.