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. 2022 Mar 29;23(7):3758. doi: 10.3390/ijms23073758

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Schematic representation of the enteroendocrine cell subpopulation in the gastrointestinal (GI) tract. EC: enterochromaffin cell; 5-HT: 5-hydroxytryptamine; CCK: cholecystokinin; GLP-1: glucagon like peptide-1; GLP-2: glucagon like peptide-2; PYY: peptide YY; GIP: gastric inhibitory peptide-1; dark red circle indicates the A cells secreting ghrelin in the stomach (corpus); purple circle indicates the G cells secreting gastrin in the stomach (antrum); red circle indicates the D cells secreting somatostatin in the stomach (pylorum); dark blue circle indicates the I cells and orange circle indicates the K cells secreting CPK and GIP in the small intestine; light blue circle indicates the L cells secreting GLP-1, GLP-2 and PYY, widely distributed in small intestine and in colon. The Figure is obtained from Latorre et al., 2016. Reprinted under the terms of the Creative Commons CC BY license [8].