Figure 2.

PLS-DA display minimal differences in metabolic profiles between diets and the respective FG supplemented diet in small intestines. Untargeted metabolomics was performed on the jejunum and ileum contents mice fed HF, HFFG, CD, or CDFFG diets for 14 weeks. PLS-DA were performed for (A) identified jejunum metabolites, (B) all jejunum spectral features, (C) identified ileum metabolites, and (D) all ileum spectral features. Cross validation values can be found in Supplementary Table S1. Experimental replicates are shown; HF samples are shown in red, HFFG samples are shown in red stripes, CD samples are shown in blue, and CDFG samples are shown in blue stripes.