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. 2022 Mar 26;23(7):3654. doi: 10.3390/ijms23073654

Table 1.

Summary of identified metabolites and unidentified mass spectral features from metabolomics data. Only features with p-values less than 0.05 and fold change greater than 1.5 or less than 0.667 were counted as significantly increased with fenugreek. Features with p-value less than 0.05 and fold change (HFFG/HF) less than 0.667 were counted as significantly decreased with fenugreek.

High Fat Diet Metabolomics
Jejunum Ileum Cecum Colon Liver Serum
Total identified metabolites 145 140 141 137 130 120
HF-altered 11 2 41 30 2 7
HF vs. CD increased w/HF 5 0 35 9 0 6
decreased w/HF 6 2 6 21 2 1
HF-altered & FG-altered 6 4 1 6 3 0
CD vs. CDFG increased w/FG 2 4 0 0 1 0
decreased w/FG 4 0 0 0 2 0
HF vs. HFFG increased w/FG 0 0 0 5 0 0
decreased w/FG 0 0 1 1 0 0
Total unique spectral features 6837 6823 11157 8974 3323 1772
HF-altered 594 718 4294 2809 339 105
HF vs. CD increased w/HF 114 508 3671 1977 59 94
decreased w/HF 480 210 623 832 280 11
HF-altered & FG-altered 104 473 2917 1913 111 37
CD vs. CDFG increased w/FG 18 0 1685 1243 0 16
decreased w/FG 72 255 678 282 23 2
HF vs. HFFG increased w/FG 12 11 217 238 51 8
decreased w/FG 6 310 992 515 37 13