Table 1.
Sample groups and statistics of nodes in integrated datasets collected from RNA-Seq datasets of Gene Expression Omnibus (GEO) database (accession nos. GSE156063 and GSE163151).
| Datasets | GSE163151 | GSE156063 | Integrated | Group Definition | |
| Sample | |||||
| COVID-19-associated ARDS | 138 | 93 | 231 | ARDS patients caused by SARS-CoV-2 infection | |
| Non-viral ARDS | 82 | 100 | 182 | ARDS patients not caused by viral infection (including SARS-CoV-2) | |
| Datasets | GSE163151 | GSE156063 | Integrated | Node Description | |
| Nodes | |||||
| Protein | 17055 | 12929 | 18225 | Nodes with unknown functions (excluding Rcp, TF, miRNA, LncRNA, and Virus) are assumed to express protein. | |
| Rcp | 2484 | 1700 | 2500 | Receptor | |
| TF | 1502 | 1216 | 1519 | Transcription factor | |
| RcpTF | 105 | 89 | 105 | Nodes with both Rcp and TF function | |
| miRNA | 1378 | 0 | 1378 | miRNA | |
| LncRNA | 2781 | 35 | 2784 | LncRNA | |
| Virus | 0 | 13 | 13 | SARS-CoV-2 nodes (please refer to Table S1 for detail) | |
| Total | 24309 | 15982 | 26524 | ||
NOTE: Nodes are proteins/genes that have at least 1 interaction with others in the network. For the convenience of analysis, nodes are classified into 7 classes (Protein, Rcp, TF, RcpTF, miRNA, LncRNA, Virus) in this study.