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Selected drugs and their corresponding drug targets in the multiple-molecule drug therapy for COVID-19-associated ARDS.
| Targets | TNF | NFkB | HIF1A | GRP78 | FTO | BECN1 | ||
|---|---|---|---|---|---|---|---|---|
| Drugs | ||||||||
| Nicorandil | ⬤ | ⬤ | ⬤ | |||||
| Isoliquiritigenin | ⬤ | ⬤ | ⬤ | |||||
| Eugenol | ⬤ | ⬤ | ||||||
| Omeprazole | ⬤ | ⬤ | ⬤ | ⬤ | ||||
| Chemical structures of multiple-molecule drug | ||||||||
| Nicorandil | Isoliquiritigenin | |||||||
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| Eugenol | Omeprazole | |||||||
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⬤: The proposed small molecules to target the biomarkers (drug targets).
