Table 5.

ENPP2 DMCs identified in ccfDNA of BrCa patients and healthy individuals via in silico analysis.

CG ID	Mβ Value BrCa	Mβ Value Normal	ΔβValue	Methylation in BrCa	Location	FDR
cg07236691	0.583	0.817	−0.234	Down	Body	3.04 × 10−3
cg20048037	0.711	0.331	0.380	Up	Body	5.08 × 10−5
cg20162626	0.489	0.814	−0.325	Down	Body	3.18 × 10−4
cg02534163	0.802	0.206	0.596	Up	1st Exon	6.30 × 10−11
cg04452959	0.620	0.020	0.599	Up	TS200	2.51 × 10−13
cg02156680	0.515	0.028	0.487	Up	TSS1500	1.48 × 10−13
cg06998282	0.772	0.057	0.715	Up	TSS1500	1.61 × 10−8
cg14409958	0.748	0.053	0.695	Up	TSS1500	2.24 × 10−6

Abbreviations: BrCa: breast cancer, DMCs: differentially methylated CpGs, FDR: false discovery rate, Mβ Value: mean β value, Δβ Value: difference between mean values.