Time-kill curves of polygodial comparing S.
cerevisiae W303-1a to petite mutants, which are respiration
deficient, in RPMI 1640 with MOPS (pH 7) plus 2% glucose. Results for
controls are represented with filled symbols, and those for
polygodial-treated cells are represented with open symbols as follows:
● and ○, W303-1a; ▾ and ▿, [rho−]
strain; and ■ and □, [rho0] strain.
Concentrations of polygodial were 6.25 μg/ml (A) and 3.13 μg/ml
(B).