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. 2022 Mar 30;23(7):3818. doi: 10.3390/ijms23073818

Figure 2.

Figure 2

EGFR mutations and gene fusions in HNSCC patients curated in the cBioPortal for Cancer Genomics in relation to EGFR exons and EGFR protein domains. The table shows details of the specific mutations and corresponding patients, including protein change, exon location, functional annotation according to OncoKB precision oncology knowledge base, type of mutation, EGFR gene copy number, mutation site, nucleotide change (reference [Ref] vs. variant [V]), Human Genome Variation Society genomic nomenclature (HGVSg), tumor grade, tumor, stage, HPV subtype (+, positive; −, negative). EGFR mutational and clinical data were visualized, analyzed, and downloaded from the cBioPortal for Cancer Genomics (https://www.cbioportal.org; accessed on 19 March 2022 [22,23]).