Table 1.
Bibliographic data concerning the relationship between vWF/ADAMTS13 in preeclampsia/HELLP syndrome (PE = preeclampsia, HP = Healthy pregnancy, NP = non-pregnancy).
| Authors (Publication Date) | Sample | n | Control Group | n | vWF | ADAMTS13 |
|---|---|---|---|---|---|---|
| Kalem et al. (2017) [13] | PE | 12 | HP | 24 | Decrease | |
| Chen et al. (2021) [24] | PE | 54 | HP NP |
33 | Hyperadhesive |
Decrease Decrease |
| Stepanian et al. (2011) [14] | PE | 140 | HP | 140 | No difference | Decrease |
| Alpoim et al. (2011) [15] | PE | 55 | HP NP |
35 50 |
Increase Increase |
Decrease Decrease |
| Sabau et al. (2016) [16] | HELLP | 16 | - | <30% in 13% | ||
| Molvarec et al. (2009) [19] | PE | 67 | HP NP |
70 59 |
Normal multimeric pattern of vWF Increased vWF:Ag |
No difference |
| Yoshida et al. (2017) [20] | PE HELLP |
5 8 |
HP | 128 | Increased vWF:Ag | No difference |
| Aref et al. (2013) [2] | PE | 110 | HP NP |
50 10 |
Increase | Decrease |
| Xiao et al. (2017) [17] | PE | - | Decrease | |||
| Hulstein et al. (2006) [18] | HELLP | 14 | HP PE |
9 6 |
Increase Increase |
Decrease No difference |
| von Krogh et al. (2015) [21] | PE | 500 | HP | 500 | No difference (levels, genotype, allele, haplotype, levels) |
|
| Drury Stewart et al. (2014) [23] | NP | 46 | - | vWF: Ag increase vWFpp increase (later stage) No high molecular weight vWF multimers |
||
| Molvarec et al. (2009) [22] | PE | 93 | HP | 127 | Increase |