ALL	acute lymphoblastic leukemia
AIEOP-BFM ALL	Associazione Italiana di Ematologia Oncologia Pediatrica-Berlin-Frankfurt-Münster Acute Lymphoblastic Leukemia
AKT	serine/threonine kinase
AML	acute myeloid leukemia
ATF4	cyclic AMP-dependent transcription factor
Bad	Bcl-2-associated agonist of cell death
Bak	Bcl-2 homologous antagonist/killer
Bax	Bcl-2-associated X-protein 4
Bcl-2	B-cell lymphoma 2
Bcl-w	B-cell lymphoma-w
Bcl-XL	B-cell lymphoma extra-large
Bid	BH3 interacting-domain death agonist
BIM	Bcl-2-interacting mediator of cell death
cAMP-PKA	cyclic adenosine monophosphate-dependent protein kinase
CASP1	caspaze 1
CBD	cannabidiol
CHOP	C/EBP Homologous Protein
CI	combination index
CNS	central nervous system
CR	complete response
CRLF2	cytokine receptor-like factor 2
dmPGE2	6,16-dimethyl-prostaglandin E2
DN	double negative
DR	death receptor
EFS	event-free survival
EMA	European Medicines Agency
ER	extreme risk
ERK	extracellular signal-regulated kinase
ESRRB	orphan nuclear receptor estrogen-related receptor-b
ETP	early T-cell progenitor
FBXW7	F-Box and WD Repeat Domain-Containing 7
FDA	Food and Drug Administration
FKBP51	FK506-binding protein 51
FOXO3a	forkhead box O3
GR	glucocorticoid receptor
GRE	glucocorticoid response element
GSK3	glycogen synthase kinase-3
GTG	glucocorticoid target gene
HR	high risk
Hrk	activator of apoptosis harakiri
HyperCVAD	hyperfractionated cyclophosphamide, vincristine, doxorubicin, dexamethasone
IC50	half maximal inhibitory concentration
IGR	intronic GR binding region
IL-6	interleukin 6
IL-7	interleukin-7
IL-7R	IL-7 receptor
JAK	Janus kinases
LC50	median lethal concentration
MAPK	mitogen-activated protein kinase
Mcl-1	induced myeloid leukemia cell differentiation protein
miRNA	microRNA
MLL	mixed lineage leukemia
MRD	minimal residual disease
mRNA	messenger RNA
mTOR	mammalian target of rapamycin kinase
NF-κB	nuclear factor-κB
NOD	nonobese diabetic
Notch	neurogenic locus notch homolog protein
Noxa	phorbol-12-myristate-13-acetate-induced protein 1
OXPHOS	oxidative phosphorylation
PERK	protein kinase R -like endoplasmic reticulum kinase
PGR	prednisolone good response
Ph-like	Philadelphia chromosome-like
PI3K	phosphatidylinositol 3-kinase
PKR	protein kinase R
PPR	prednisolone poor response
pre-B ALL	precursor-B-cell ALL
Puma	p53-upregulated modulator of apoptosis
Raf	rapidly accelerated fibrosarcoma
Ras	rat sarcoma virus
RER	endoplasmic reticulum
ROS	reactive oxygen species
RT-PCR	real-time polymerase chain reaction
SCID	severe combined immunodeficiency
SE	survival estimates
shRNA	short hairpin RNA
SIRT1	sirtuin 1
SR	standard risk
STAT	signal transducer and activator of transcription
T-ALL	precursor T-cell ALL
T-LL	T-lymphoblastic lymphoma
TNF	tumor-necrosis-factor
TRB3	tribbles homolog 3
VDAC	voltage-dependent anion channel 1
VXL	vincristine, dexamethasone and L-asparaginase
γc	γ chain
Δ9-THC	Δ9-tetrahydrocannabinol