Table 1.
Patient characteristics and HF treatments at baseline.
| N(%) or Median (q1;q3) | Jet Echo N = 127 | Standard Care N = 121 | p-Value * |
|---|---|---|---|
| Baseline characteristics | |||
| Age at inclusion (y) | 75 (66;82) | 76 (64;84) | 0.57 |
| Female | 38 (30%) | 36 (30%) | 0.98 |
| BMI (q1;q3) | 27.05 (24.2;30.7) | 27.35 (24.1;31.1) | 0.66 |
| Hypertension | 83 (65%) | 85 (70%) | 0.41 |
| Diabetes | 54 (43%) | 43 (36%) | 0.26 |
| Smoker | 17 (13%) | 23 (19%) | 0.23 |
| Atrial fibrillation | 45 (35%) | 53 (44%) | 0.32 |
| Ischemic Cardiomyopathy | 53 (42%) | 52 (43%) | 1.00 |
| Clinical parameters | |||
| NYHA functional class | 0.90 | ||
| stage (I, II) | 7 (5%) | 5(4%) | |
| stage III | 33 (26%) | 33 (28%) | |
| stage IV | 87 (69%) | 82 (68%) | |
| Sinus Rhythm | 85 (67%) | 61 (50%) | 0.01 |
| Heart rate (bpm) | 87 (72;106) | 82 (72;102) | 0.22 |
| SBP (mmHg) | 126 (112;141) | 125 (110;139) | 0.52 |
| DBP (mmHg) | 75 (67;89) | 76 (67;86) | 0.52 |
| LVEF (%) | 0.81 | ||
| <40% | 97(76%) | 94 (78%) | |
| 40–49% | 30 (24%) | 27 (22%) | |
| Types of HF | 0.53 | ||
| Global | 68 (54%) | 71 (59%) | |
| Right | 6 (5%) | 3 (2%) | |
| Left | 53 (42%) | 47 (39%) | |
| Laboratory | |||
| Nt-proBNP (ng/L) | 6460 (3551;12,336) | 6099 (3335.5;12,457) | 0.55 |
| Troponin (ng/L) | 51.7 (32;184.1) | 43.9 (27.7;101.8) | 0.22 |
| eGFR (ml/min) | 52 (39;66.1) | 50 (37;66) | 0.76 |
| BUN (mmol/L) | 9 (6.8;13.8) | 8.3 (6.5;13.2) | 0.55 |
| Natremia (mM) | 140 (137;143) | 141 (138;143) | 0.42 |
| Kaliemia (mM) | 4.2 (3.8;4.6) | 4.1 (3.8;4.5) | 0.35 |
| Haemoglobin (g/dL) | 12.6 (11.3;14.1) | 13 (11.5;14.7) | 0.16 |
| Treatment on admission | |||
| Diuretic | 23 (18%) | 23 (19%) | 0.86 |
| Beta-blocker | 70 (55%) | 63 (52%) | 0.63 |
| ACE inhibitor | 50 (39%) | 39 (32%) | 0.24 |
| ARB | 21 (17%) | 19 (16%) | 0.86 |
| MRA | 21 (17%) | 12 (10%) | 0.13 |
| ICD | 16 (13%) | 11 (9%) | 0.41 |
| CRT | 9 (7%) | 4 (3%) | 0.25 |
* p-value: Chi-square or Fisher for qualitative variable; Student or Wilcoxon for continuous. Abbreviations: ACE, angiotensin-converting enzyme; ARB, angiotensin II receptor blocker; BMI, body mass index; BUN, blood urea nitrogen; CRT, cardiac resynchronization therapy; DBP, diastolic blood pressure; eGFR, glomerular filtration rate; HF, heart failure; ICD, intracardiac defibrillator; LVEF, left ventricular ejection fraction; RA, mineralocorticoid antagonist; NT-pro-BNP: N-terminal-pro-B-type natriuretic peptide; NYHA, New York Heart Association; SBP, systolic blood pressure; SC, standard of care.