Figure 5.

(A). Luteolin treatment inhibits colony formation in a dose-dependent manner with almost no colonies at 20 µM luteolin treatment for 48 h. The values plotted are mean of three experiments ± SD (* represents that data is statistically significant with p ≤ 0.05). (B). Luteolin treatment inhibits migration of HeLa cells in a dose-dependent manner, as compared with control wells, wherein almost complete wound closure could be seen after 48 h. (C). The luteolin-treated HeLa cells depicted significant decrease in cell migration using transwell inserts. Microscopic images at 10× magnification showing migrated cells in control and the migration at 10 and 20 µM of luteolin treatment for 48 h.