Relationship between endotoxin levels and ADAMTS13:AC, endotoxin levels and VWF:Ag, and endotoxin levels and VWF:Ag/ADAMTS13:AC. (a) Patients with endotoxin levels of >5 pg/mL had lower ADAMTS13:AC than those with endotoxin levels of ≤5 pg/mL (p < 0.05). (b) Patients with endotoxin levels of >5 pg/mL had higher VWF:Ag than those with endotoxin levels of ≤5 pg/mL (p < 0.05). (c) Patients with endotoxin levels of >5 pg/mL had higher VWF:Ag/ADAMTS13:AC than those with endotoxin levels of ≤5 pg/mL (p < 0.05). Box plots represent, from top to bottom, sample maximum, upper-quartile range, median and lower-quartile range, and sample minimum. ADAMTS13, a disintegrin-like and metalloproteinase with thrombospondin type 1 motifs 13; ADAMTS13:AC, ADAMTS13 activity; VWF, von Willebrand factor; VWF:Ag, VWF antigen; VWF:Ag/ADAMTS13:AC, ratio of VWF:Ag to ADAMTS13:AC.