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. 2022 Mar 28;9:821509. doi: 10.3389/fsurg.2022.821509

Table 2.

Distribution of risk factors in the overall population and within the subgroups of early and late closure.

Total [n = 409] Closure <150 days [n = 229] Closure > 150 days [n = 180] p-value
Age [M (SD)] 59.5 years (13.1 years) 57.5 years (14.6 years) 60.3 years (11.0 years) 0.028*
Age groups [% ( n )] 0.122 (ns)
<60 years 45.97 (188) 49.34 (113) 41.67 (75)
>60 years 54.03 (221) 50.66 (116) 58.33 (105)
Sex [% ( n )] 0.630 (ns)
Men 72.13 (295) 71.18 (163) 73.33 (132)
Women 27.87 (114) 28.82 (66) 26.67 (48)
Primary diagnosis[% ( n )] 0.001**
Rectal cancer 73.35 (300) 65.50 (150) 83.33 (150) <0.001**
Ulcerative colitis 13.20 (54) 17.90 (41) 7.22 (13) 0.002*
Peritoneal carcinomatosis 7.58 (31) 10.04 (23) 4.44 (8) 0.034*
Sigmoid (colon) cancer 5.87 (24) 6.55 (15) 5.00 (9) 0.508 (ns)
Primary surgery[% ( n )] 0.491 (ns)
Colectomy, hemicolectomy, sigma resection 7.34 (30) 7.42 (17) 7.22 (13) 0.938 (ns)
Extraperitoneal rectum resection (cytoreductive surgery) 3.42 (14) 4.37 (10) 2.22 (4) 0.236 (ns)
Low anterior rectum resection, proctocolectomy 89.24 (365) 88.21 (202) 90.56 (163) 0.447 (ns)
Reconstruction[% ( n )] 0.277 (ns)
End to end 84.60 (346) 88.65 (203) 79.44 (143)
Side to side 11.25 (48) 10.04 (24) 12.78 (24)
Suture technique[% ( n )] 0.359 (ns)
Running suture 91.93 (376) 94.76 (217) 88.33 (159)
Single stitches 2.44 (10) 3.06 (7) 1.67 (3)
Stapler 0.49 (2) 0.87 (2) 0 (0)
Adjuvant chemotherapy [% (n)] 49.88 (204) 28.33 (97) 59.44 (107) 0.014*

Missing documentation about surgical reconstruction; *p < 0.05, **p < 0.001.