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Overview of pathomechanisms involved in Brugada syndrome [9,10,11,12,21,22,24,25,26,27]. Abbreviations: AT—antithrombin; BrS—Brugada syndrome; Ca2+—calcium; ECG—electrocardiogram; K+—potassium; ICD—implantable cardioverter–defibrillator; Na+—sodium; SCD—sudden cardiac death; SCN5A—sodium voltage-gated channel alpha subunit 5; RV—right ventricle; RVOT—right ventricular outflow tract; VF—ventricular fibrillation; VT—ventricular tachycardia.
