Table 1.
Baseline clinicodemographic characteristics of the study patients.
| Esomeprazole | Esomeprazole + Mosapride | p Value | |
|---|---|---|---|
| (n = 30) | (n = 30) | ||
| Age, years | 34.7 ± 13.2 | 38.2 ± 14.0 | 0.323 |
| Sex | 0.381 | ||
| Man | 6 (20.0) | 10 (33.3) | |
| Woman | 24 (80.0) | 20 (66.7) | |
| Height, cm | 163.2 ± 7.3 | 163.2 ± 10.3 | 1.000 |
| Body weight, kg | 59.5 ± 10.3 | 60.6 ± 10.6 | 0.685 |
| Body-mass index, kg/m2 | 22.2 ± 7.0 | 22.9 ± 7.3 | 0.685 |
| Waist, cm | 73.1 ± 7.9 | 72.9 ± 10.6 | 0.916 |
| Alcohol drinking | 26 (86.7) | 26 (86.7) | 1.000 |
| Smoking | 2 (6.7) | 7 (23.3) | 0.148 |
| GERD-symptom scores | |||
| RDQ score | 36.7 ± 21.1 | 31.3 ± 17.0 | 0.285 |
| GERD-HRQL score | 15.8 ± 7.6 | 14.7 ± 6.3 | 0.543 |
| Reflux esophagitis | 1.000 | ||
| Absent | 23 (76.6) | 22 (73.3) | |
| Present | 7 (23.3) | 8 (26.7) | |
| Hiatal hernia | 1.000 | ||
| Absent | 28 (93.3) | 29 (96.7) | |
| Present | 2 (6.7) | 1 (3.3) | |
| Atrophic gastritis | 0.731 | ||
| Absent | 6 (20.0) | 4 (13.3) | |
| Closed type | 24 (80.0) | 25 (83.3) | |
| Open type | 0 | 1 (3.3) | |
| Helicobacter pylori infection | 0.424 | ||
| Absent | 28 (93.3) | 25 (83.3) | |
| Present | 2 (6.7) | 5 (16.7) |
Data are presented as mean ± standard deviation or number (%). GERD, gastroesophageal reflux disease; HRQL, health-related quality of life; RDQ, reflux-disease questionnaire.