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. 2022 Mar 27;15(7):2472. doi: 10.3390/ma15072472

Figure 2.

Figure 2

Solubility of caffeine, expressed as its mole fractions, in binary solvents comprising water and one of five studied aprotic proton acceptor solvents in varying compositions. On the abscissa, x2* represents the mole fractions of organic solvent in solute-free binary solutions.