Skip to main content
. 2022 Apr 11;17(4):e0266800. doi: 10.1371/journal.pone.0266800

Table 4. Summary of modifications to the prototype V2 from usability tests.

  • The term “health-based guidance value” was used to describe an upper or lower limit of exposure to or consumption of a substance. Risk assessors stated that this term described relevant threshold values, such as the Acceptable and the Tolerable Daily Intake (ADI and TDI), in non-expert terms. Where an upper and lower limit of exposure was relevant (e.g., consuming an amount of fish to increase health benefits while limiting mercury exposure), both limits should be described, similar to Fig 4B.
  • The safety area was removed from the health-based guidance value visual as risk assessors stated that the size of a possible safety area could not be measured. Rather, the difference between the no observable adverse effect level and the upper limit of exposure should be communicated as an uncertainty interval (see Figs 4 and 5)
  • For quality of evidence, details about the type or source of available evidence (e.g. animal studies, expert opinions, cell studies etc) were described.
  • Minor edits were made to the wording of different categories (e.g., the controllability dimension “How can the risk be minimized” was changed to “How can the risk be reduced”).