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Proposed downstream signaling pathways for GPR37 and GPR37 L1. (Gi/o = G alpha i/o subunit; AC = adenylyl cyclase; cAMP = cyclic AMP; ERK = extracellular signal-regulated kinase, P = phosphate; PLC = phospholipase C; Gq/11 = G alpha q/11 subunit; IP3 = inositol trisphosphate; DAG = diacylglycerol, Ca2+ = calcium). Image created with BioRender.com (accessed on 26 March 2022).
