Table 1.
Classification of epithelial cell layer properties, stromal hyperreflective keratocytes, stromal hyperreflective spikes and endothelial cell layer properties. We used a classification modified from Aragona et al. [54].
| Epithelial Cell Layer Hyperreflectivity/Micrograph | Number of Stromal Hyperreflective Keratocytes/Micrograph | Number of Stromal Hyperreflective Spikes/Micrograph | Endothelial Cell Layer | |
|---|---|---|---|---|
| 0 | - | no changes | no changes | - |
| 1 | no changes | ≤4 | ≤1 | no changes |
| 2 | ≤4 | 5–7 | 2–3 | hyperreflective changes |
| 3 | >4 | 8–16 | ≥4 | guttae |
| 4 | no images for evaluation | >16 | giant spike/s (>75 µm) | no images for evaluation |
| 5 | - | no images for evaluation | no images for evaluation | - |