Table 3.
Number (%) of eyes with monoclonal gammopathy and number (%) of control eyes in groups 0–5, concerning epithelial cell layer properties, number of hyperreflective stromal keratocytes and hyperreflective stromal spikes per micrograph and endothelial cell layer properties. p values show results of the statistical analysis using χ2 test. The arbitrary scoring system, described in Table 1, has been used. * Significantly higher in controls, as in MG subjects.
| Epithelial Cell Layer Hyperreflectivity/Micrograph | Number of Stromal Hyperreflective Keratocytes/Micrograph | Number of Stromal Hyperreflective Spikes/Micrograph | Endothelial Cell Layer | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Anterior Stroma | Middle Stroma | Posterior Stroma | Anterior Stroma | Middle Stroma | Posterior Stroma | ||||
| MG | 0 | - | 0 | 1 (0.8%) | 0 | 77 (59.2%) | 55 (42.3%) | 36 (27.7%) | - |
| 1 | 71 (54.6%) | 2 (1.5%) | 2 (1.5%) | 0 | 28 (21.5%) | 42 (32.3%) | 42 (32.3%) | 64 (49.2%) | |
| 2 | 41 (31.5%) | 20 (15.4%) | 12 (9.2%) | 10 (7.7%) | 5 (3.8%) | 17 (13.1%) | 26 (20.0%) | 39 (30.0%) | |
| 3 | 10 (7.7%) | 35 (26.9%) | 55 (42.3%) | 48 (36.9%) | 9 (6.9%) | 11 (8.5%) | 19 (14.6%) | 12 (9.2%) | |
| 4 | 8 (6.2%) | 61 (46.9%) | 54 (41.5%) | 59 (45.4%) | 1 (0.8%) | 1 (0.8%) | 0 | 15 (11.5%) | |
| 5 | - | 12 (9.2%) | 6 (4.6%) | 13 (10.0%) | 10 (7.7%) | 4 (3.1%) | 7 (5.4%) | - | |
| Controls | 0 | - | 0 | 1 (1.0%) | 0 | 66 (66.0%) | 76 (76.0%) | 62 (62.0%) | - |
| 1 | 29 (29.0%) | 15 (15.0%) | 13 (13.0%) | 16 (16.0%) | 11 (11.0%) | 16 (16.0%) | 20 (20.0%) | 44 (44.0%) | |
| 2 | 38 (38.0%) | 42 (42.0%) | 44 (44.0%) | 28 (28.0%) | 1 (1.0%) | 2 (2.0%) | 1 (1.0%) | 24 (24.0%) | |
| 3 | 25 (25.0%) | 21 (21.0%) | 40 (40.0%) | 45 (45.0%) | 18 (18.0%) | 6 (6.0%) | 14 (14.0%) | 22 (22.0%) | |
| 4 | 8 (8.0%) | 19 (19.0%) | 2 (2.0%) | 8 (8.0%) | 1 (150%) | 0 | 0 | 10 (10.0%) | |
| 5 | - | 3 (3.0%) | 0 | 3 (3.0%) | 3 (3.0%) | 0 | 3 (3.0%) | - | |
| p value | <0.001 * | <0.001 | <0.001 | <0.001 | 0.015 | <0.001 | <0.001 | 0.059 | |