TABLE 2.
In vitro activities of 15 antimicrobial agents against 27 clinical isolates of D. pigrum by broth dilutiona
| Drug | MICb (μg/ml)
|
% Resistant strains | ||
|---|---|---|---|---|
| Range | 50% | 90% | ||
| Penicillin | ≤0.03 | ≤0.03 | ≤0.03 | 0 |
| Amoxicillin | ≤0.03 | ≤0.03 | ≤0.03 | 0 |
| Cefotaxime | 0.06–0.25 | 0.06 | 0.12 | 0 |
| Cefuroxime | 0.12–0.25 | 0.12 | 0.12 | 0 |
| Meropenem | ≤0.06 | ≤0.06 | ≤0.06 | 0 |
| Erythromycin | 0.12–2.0 | 1.0 | 1.0 | 52 |
| Trimethoprim-sulfamethoxazole | 0.12–8.0 | 0.12 | 0.5 | 4c |
| Clindamycin | 0.06–0.25 | 0.06 | 0.25 | 0 |
| Chloramphenicol | 2.0–8.0 | 8.0 | 8.0 | 0 |
| Levofloxacin | 0.06–1.0 | 0.06 | 0.06 | 0 |
| Trovafloxacin | ≤0.25 | ≤0.25 | ≤0.25 | 0 |
| Vancomycin | 0.12–0.5 | 0.12 | 0.12 | 0 |
| Rifampin | ≤1.0 | ≤1.0 | ≤1.0 | 0 |
| Tetracycline | ≤1.0 | ≤1.0 | ≤1.0 | 0 |
| Quinupristin-dalfopristin | ≤1.0 | ≤1.0 | ≤1.0 | 0 |
a
Interpretive standards for Streptococcus spp. other than S. pneumoniae were used.
b
50% and 90%, MICs at which 50 and 90% of isolates, respectively, were inhibited.
c
Interpretive standards for S. pneumoniae were used.