Table 2.
Level of evidence | Description |
---|---|
1 | High-quality, multi-centered or single-centered, prospective cohort or comparative study with adequate power; or a systematic review of these studies |
II | Lesser-quality prospective cohort or comparative study; retrospective cohort or comparative study; untreated controls from a randomized controlled trial; or a systematic review of these studies |
III | Case-control study; or systematic review of these studies |
IV | Case series with pre-/post-test; or only post-test |
V | Expert opinion developed via consensus process; case report or clinical example; or evidence based on physiology, bench research or “first principles” |