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. 2022 Mar 22;27(7):2041. doi: 10.3390/molecules27072041

Figure 1.

Figure 1

Key pathways of chemokines’ oncogenic effect. MAPK/Erk—mitogen-activated protein kinase/extracellular signal-regulated kinase; PI3K—phosphoinositide 3-kinase; NF-κB—nuclear factor kappa-B; IL-8—interleukin 8; VEGF—vascular endothelial growth factor; MMP2/9—metalloproteinases 2 and 9; EMT—epithelial–mesenchymal transition.