Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mechanism for the neuroprotective effect of crocin in depression. Stress can cause depression (A), however, saffron crocin can reduce the effect of stress by exhibiting neuroprotection activity (B). PACAP, pituitary adenylate cyclase-activating polypeptide; ERK, extracellular regulated protein kinases; CREB, response element binding protein; cAMP, cyclic adenosine monophosphate; ATP, adenosine triphosphate; AC, adenylyl cyclase [98].
