Table 4.
Multiple linear regression model showing the association among changes (post-pre) in sex hormones and cognitive functions and functional level, in both groups.
| Variables | Experimental group | Control group | ||||||
|---|---|---|---|---|---|---|---|---|
| RUDAS | FIM | RUDAS | FIM | |||||
| B | p value | B | p value | B | p value | B | p value | |
| Estradiol (pg/ml) | 0.139 | 0.479 | 0.492 | 0.363 | .121 | 0.449 | 0.699 | 0.041∗ |
| Total testosterone (ng/ml) | -10.056 | 0.253 | -10.712 | 0.654 | -7.095 | 0.603 | 18.995 | 0.501 |
| Free testosterone (pg/ml) | 1.085 | 0.205 | -2.802 | 0.232 | 1.580 | 0.108 | 2.882 | 0.153 |
| SHBG (nmol/ml) | 0.046 | 0.734 | 0.168 | 0.650 | 0.173 | 0.458 | 0.868 | 0.079 |
Values are presented as beta coefficient and p value of each parameter. ∗p value <0.05 is considered statistically significant according to multiple regression analysis. FIM: functional independence measure; RUDAS: Rowland Universal Dementia Assessment Scale; SHBG: sex hormone binding globulin.