Table 1.
P-value for top biological pathways after FDR sorting for M HFD vs F HFD and M ND vs M HFD.
| Pathway name | M ND vs M HFD | M HFD vs F HFD |
|---|---|---|
| Lysosome | 3.32E-20 | 3.20E-16 |
| Phagosome | 7.66E-10 | 3.78E-9 |
| Metabolic pathways | 2.82E-8 | 3.40E-8 |
| Hematopoietic cell lineage | 1.83E-4 | 1.41E-7 |
| Cell adhesion molecules | 5.09E-6 | 5.55E-7 |
| Rap1 signaling pathway | 8.68E-7 | 5.75E-7 |
| Pathways in cancer | 1.90E-6 | 1.23E-6 |
| Fluid shear stress and atherosclerosis | 4.87E-6 | 6.25E-6 |
| Glutathione metabolism | 2.75E-4 | 7.21E-6 |
| PI3K-Akt signaling pathway | 1.10E-5 | 9.58E-6 |
| Focal adhesion | 4.20E-5 | 9.58E-6 |
| Salivary secretion | 5.10E-4 | 1.72E-5 |
| Axon guidance | 5.57E-5 | 2.00E-5 |
| Tuberculosis | 5.09E-6 | 3.91E-5 |
| Transcriptional mis-regulation in cancer | 5.19E-5 | 4.37E-5 |
| Amoebiasis | 3.20E-6 | 4.58E-5 |
| cGMP-PKG signaling pathway | 3.30E-3 | 4.87E-5 |
| Rheumatoid arthritis | 1.49E-4 | 7.42E-5 |
| Aldosterone synthesis and secretion | 1.42E-4 | 7.94E-5 |
| Leukocyte trans-endothelial migration | 1.54E-4 | 7.94E-5 |
| Cytokine-cytokine interaction | 4.55E-4 | 1.02E-4 |
| Ferroptosis | 1.59E-3 | 1.09E-4 |
| Gastric acid secretion | 5.49E-4 | 1.46E-4 |
| Vascular smooth muscle contraction | 2.30E-3 | 1.81E-4 |
| NF-kappa B signaling pathway | 1.10E-5 | 1.82E-4 |