TABLE 2.

Parameter values for four rabbits dosed with 5 mg of ABLC per kg via a 5-min infusion based on best-fit curves from concentrations determined in whole blood and plasma

Parameter	Rabbit A	Rabbit B	Rabbit C	Rabbit D	Mean (CVc)
L(3,2) (h−1)	1,600	3,200	4,812	2,260	2,968 (47)
L(2,3) (h−1)	10.84	16.49	10.60	5.06	10.74 (43)
L(6,2) (h−1)	163.2	297	342	188	247.6 (34)a
P(2)b	1.97	3.70	4.68	1.97	3.08 (32)a
P(3) (h−1)	9.9 × 10−4	8.0	9.9 × 10−4	9.9 × 10−4	2.02 (197)
P(4) (h−1)	1,678	96.14	1.36	1,678	847.9 (108)
P(6) (h−1)	2.8 × 10−3	2.3 × 10−2	2.8 × 10−3	2.3 × 10−2	0.014 (93)a
P(10) (h−1)	1.62 × 10−5	4.72	1.62 × 10−5	1.62 × 10−5	1.18 (199)
P(12) (h−1)	63	58.04	51.51	52.1	56.2 (9.7)
P(13) (h−1)	12.5	12.0	17.87	17.75	15.0 (21)a

^aThe mean values of the parameters from these fits were used to define the red blood cell compartment for the animals from which whole blood was not collected. 

^bNo units. 

^cCV, coefficient of variation.