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Gentamicin levels in serum and peak-to-MIC ratios in rabbits with experimental endocarditis due to E. faecalis JH2-2 or BM4281
| Gentamicin dose (mg/kg) | Level in serum (μg/ml)
|
Peak/MIC ratio
|
||
|---|---|---|---|---|
| Peaka | Trough | JH2-2 | BM4281 | |
| 3 | 7.0 ± 1.3 | <0.2 | 0.4 | 1.4 |
| 6 | 17.7 ± 1.5 | <0.2 | 1.1 | 3.5 |
Means ± standard deviations.
