Table 1.

Enriched gRNAs in the MHC II^high population.

FC	log10(p value)	Gene	Name	gRNAs
6.04	7.313	March1	E3 ubiquitin-protein ligase MARCH1	2
5.82	8.362	Cbfb	Core-binding factor subunit beta	1
3.33	8.503	Ahr	Aryl hydrocarbon receptor	1
3.16	5.923	Ubl3	Ubiquitin-like protein 3	3
2.78	8.049	Kdm2b	Lysine-specific demethylase 2B	1
2.71	9.817	Runx3	Runt-related transcription factor 3	1
2.65	5.512	Ldb3	LIM domain-binding protein 3	1
2.54	6.780	Max	Protein max	1
2.51	5.556	Amn1	Antagonist of mitotic exit network 1	1
2.42	9.681	Runx1	Runt-related transcription factor 1	1
2.25	26.770	Mxi1	Max-interacting protein 1	1
2.19	9.306	Pcgf1	Polycomb group RING finger protein 1	2

P values were assessed using a negative binomial generalized linear model with a two-sided likelihood ratio test, with adjustment for multiple testing using the Benjamini–Hochberg false discovery rate (FDR) method. Shown are hits with false discovery rate <0.01 and >2-fold enrichment over the reference library. FC fold change, gRNAs number of gRNAs detected.